COVID19: Dexamethasone; death or deliverer therefrom?

Interleukin-6 prevents dexamethasone-induced myeloma cell death.

The effects of dexamethasone on the growth of four human multiple myeloma cell lines were studied. In addition, the effects on the expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) genes were investigated by the use of reverse-transcriptase polymerase chain reaction. Dexamethasone (Dex) concentrations of 10(-7) to 10(-6) mol/L inhibited IL-6 gene expression in three of four cell line...

O-6: Response to Potassium Paraaminobenzoate(PotabaTM) or Iontophoresis with Verapamiland Dexamethasone (Physion TM) inPeyronie

Induction of parturition in ewes with dexamethasone or dexamethasone and cloprostenol.

Darturition is believed to be initiated when adrenocorticotropic hormone (ACTH) from the fetal pituitary gland causes a release of cortisol from the fetal adrenal cortex (1). The fetal cortisol reduces placental progesterone production and increases placental estrogen production, resulting in release of prostaglandin F2, (PGF) from the uterus (1). Consequently, uterine activity increases, the c...

Brain death or brain dying?

For the past 50 years, the medical profession has understood ‘‘brain death’’ to represent the endpoint of a neuropathologic vicious cycle. An initial major brain injury sets off a mutually exacerbating cascade of cerebral edema, increased intracranial pressure, and decreased cerebral blood flow, which advances beyond some point-of-no-return to a state of no cerebral blood flow and total brain i...

Suspended life or extending death?